11/18/2025
Sofosbuvir is an antiviral medication that effectively treats both acute and chronic hepatic ailments known as Hepatitis C. It is a health disorder caused by the pathogen hepatitis C virus, and is characterized by the inflammation and swelling of the liver. It’s a blood-borne disease caused mainly by unsafe blood transfusions using infected needles and infections from the HIV and Hepatitis B virus. Based on the symptoms, the condition can be divided into acute and chronic forms. If these are left unaddressed, they can damage the liver tissue and lead to life-threatening conditions such as liver cancer and cirrhosis. As per the WHO, the condition led to about 240,000 mortalities in 2022 worldwide. Therefore, it becomes important to see a hepatologist at the earliest to tackle the condition.
Medical Sciences are yet to develop a vaccine for Hepatitis C, but the condition can be treated with Direct–acting antivirals (DAAs). There are various Generic Hepatitis C Drugs available on the market; however, amongst these, one of the most popular DAAs prescribed to treat Hepatitis C is Sofosbuvir 400mg Generic tablets. The medication is prescribed in combination with other antiviral drugs as deemed suitable by the hepatologist. It is essential that, before you buy Sofosbuvir 400mg Tablets online, you consult a doctor and have your health condition thoroughly analysed to ensure it is suitable for you. In the blog, we will be discussing the benefits, risks, and other helpful information associated with Sofosbuvir 400mg Tablets.
Sofosbuvir is the active ingredient found in the brand-name drug Sovaldi. It is an FDA-approved prescription drug which belongs to the drug class known as Direct–acting antivirals (DAAs), and is one of the most prescribed medications for treating Hepatitis C in adults and children aged three and above. The medication is available as oral tablets in strengths of 200mg and 400mg and as oral pellets in the strengths of 150mg and 200mg.
Sofosbuvir helps reduce viral load in Hepatitis C by acting as a barrier and inhibiting the NS5B protein, an enzyme crucial for RNA replication. For the remaining virus, the body's immune system works to eliminate it. Thereby, limits further replication and minimizes the total viral load.
Sofosbuvir 400mg tablet is taken orally once daily with or without food for a treatment span of 12 to 24 weeks. The exact duration would be suggested by your healthcare provider. The medication may be prescribed along with Ribavirin or some other antiviral.
Among children, Sofosbuvir is prescribed based on weight, with 400mg prescribed for 35kg (around 3 years old). For children weighing between 17kg and 35kg, 200mg of oral pellets or 200mg tablets may be prescribed. For those under 17kg, 150mg of oral pellets is prescribed.
Go through the medication label carefully to know all the ingredients present in this medication and inform your doctor in case you are allergic to any one of them.
Inform your doctor of all past and current health conditions, especially AIDS, diabetes, heart disease, kidney issues, and Hepatitis B. If you have been coinfected with Hepatitis B and Hepatitis C, or have previously had Hepatitis, the use of Sofosbuvir may trigger the Hepatitis B virus to reactivate.
Let your healthcare provider know of all other medications you may be taking to avoid any drug-drug interactions. Please note that taking Amiodarone along with Sofosbuvir can be lethal.
Females who are planning to get pregnant should not administer this medication. There should be a minimum gap of 6 months from the last dosage of this medication to before you start planning to get pregnant. Therefore, couples must exercise effective birth control measures to avoid getting pregnant while taking this medication.
If you are a breastfeeding mother, please discuss with your doctor about the use of Sofosbuvir.
A regular liver functioning test is prescribed to monitor the recovery from the infection or the liver’s performance while on this medication.
The medication should be taken in the manner suggested by the doctor and should not be shared with others, even with people with similar symptoms.
The side effects can be grouped into categories depending on their severity. The common side effects will go away as the body gets used to the medication; however, if they become bothersome, you must consult your doctor. A few of the common side effects have been listed below:
Headache
Tiredness
Nausea
Vomiting
Fever
Trouble falling asleep
Loss of appetite
Low red blood cell (RBC) count, also known as anaemia
The serious side effects require immediate medical care and should be brought to the notice of your healthcare team immediately. Some of the serious side effects are as follows:
Serious allergic reaction
Abnormality in the functioning of the liver
Bradycardia (or, slow heart rate)
Reactivation of the Hepatitis B virus, in those who have had this infection previously.
Sofosbuvir 400mg has revolutionized the treatment of Hepatitis, thanks to its effectiveness and positive outcomes. It has become a preferred treatment for Hepatitis C because it causes fewer side effects and requires a shorter treatment duration. It now offers an effective option that helps improve long-term liver health and enhances quality of life. However, early diagnosis is essential for treating Hepatitis C. Therefore, you should see your doctor if you notice any symptoms and follow your healthcare team's advice to manage Hepatitis C and support liver health.
Sofosbuvir, available under the brand name Sovaldi, is a prescription drug used with other antiviral drugs, such as Ribavirin, to treat chronic Hepatitis C in adults and children who are above 3 years.
The standard dose for treating Hepatitis C in adults is 400mg, taken orally once daily for 12 to 24 weeks. Children weighing 35kgs and above are put on Sofosbuvir 200mg tablets or oral pellets for 12 weeks, and those under 35kgs are prescribed 150mg of oral pellets. To know the exact dosage, please consult your healthcare specialist.
For better pricing and exclusive deals, you may purchase Sofosbuvir 400mg tablets online. However, before placing your order with any online pharmacy, it is imperative to verify the website's authenticity and legitimacy. You must look out for important info, such as their contact number, a valid license number, and accreditation from the authorizing bodies.
Sofosbuvir 400mg may cause common or serious side effects; the mild side effects will fade over time as the body builds adaptability to the medication. Examples of common side effects are: fever, headache, fatigue, sleeplessness, etc.
The severe side effects of Sofosbuvir 400mg require immediate medical care. A few symptoms of serious side effects are: reactivation of the Hepatitis B virus in those who have had or have the Hepatitis B virus, slow heart rate, unusual functioning of the liver, etc.
Sofosbuvir is usually prescribed in combination with an antiviral drug such as Ribavirin, Peginterferon, Daclatasvir, etc, to treat chronic Hepatitis C infection. Your doctor would prescribe the medication that would best suit your condition after an overall analysis of your health.
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