Ivermectin and Fenbendazole: The New Repurposed Drugs

04/30/2025

 

Ivermectin and Fenbendazole in Cancer Care

Ivermectin is an antiparasitic drug approved by the FDA. It has been effective in treating scabies, river blindness, and certain intestinal worms. However, recent studies on animals and lab evidence revealed that it possesses anti-cancer properties. It may have the potential to alter cancer cell signaling pathways and impact cell division and mitochondrial function. It could also boost the body’s immunity in the fight against cancer. A different study suggested that it could prevent tumor metastasis when used alone or in combination with other chemotherapy drugs. The efficacy of Ivermectin has been derived from its application against breast, lung, brain, urinary, blood, and digestive cancer. Its dosage varied in the laboratory depending on the study. Studies also showed that the dosage could vary based on body weight. Though Ivermectin has shown positive signs in preclinical research, conducive evidence from clinical trials is required. Later positive results on cancer patients are needed before it is approved for cancer treatment.

Fenbendazole is an antiparasitic drug approved for veterinary use. However, it is now being studied for its uses on humans. The drug gained significant attention after one of the participants in clinical trials, Joe Tippins, revealed that he was cured of small-cell lung cancer after taking it. He was prescribed fenbendazole 222mg in combination with complementary compounds such as Vit. E, Curcumin, and CBD (Cannabidiol) for three months. Later, the diagnosis showed no signs of cancer cells. Besides the anti-cancer properties, Fenbendazole has also shown evidence of an anti-tumor mechanism against various types of cancer cells. It has also helped in increasing the efficacy of other chemotherapy drugs. In addition to these, fenbendazole is also considered for cancer treatment because of its ability to disrupt energy metabolism. It has demonstrated safety and low toxicity on normal cells in animals. Fenbendazole has particularly shown very promising results against pancreatic cancer by restricting its growth and spread. Though these studies have shown positive results, most are still underway in the preclinical and observatory phases. Most of the results from these studies have been derived from animals and In-Vitro models.

The studies revealed that Ivermectin and Fenbendazole, when taken in conjunction with other supplements like Vitamin E, curcumin, and CBD, demonstrated positive results against various types of cancer. They also revealed that they maximized the immune system's ability to detect and target cancer cells, further aiding cancer recovery. They also limited the uncontrolled division of cancer cells. In addition to the medications above, advanced supplements, effective lifestyle, and dietary changes complemented the results.

Various Stages of Drugs for Cancer Care

Before researchers approve a drug for cancer, it must undergo numerous stages. Let’s know these stages before the drug is approved for public use.

1. Pre-Clinical Research

This phase involves studies on cancer cells and animals. Researchers observe the non-cancer drug’s impact on cancer cells and whether it shows promising signs of being a potential treatment. Once they see a positive outcome, the drugs are tested on animals to check their efficacy and safety.

2. Clinical Trials

This phase involves four stages, which are mentioned below:

Phase I

This phase mainly focuses on determining the dosage and its impact on cancer patients.

Phase II

This phase involves focusing on whether the new drug is effective against a specific type of cancer.

Phase III

In this phase, the results of the new drugs being studied are compared with those of existing treatments. The results are monitored to determine whether the new drug yields a better outcome.

Phase IV

This includes monitoring the impact of drugs, their side effects, and the benefits after their approval for use.

3. Post Market Surveillance

This involves continuously monitoring the drug’s impact on a larger population and its side effects, as well as determining what measures could be taken to minimize the side effects and boost the drug's efficacy.

Few Precautionary Measures

Before you start administering Ivermectin and Fenbendazole against any type of cancer, you must follow the guidelines below to minimize the risks associated with them.

• Since the medication is still being studied and hasn’t been approved by the FDA, you must only take this drug under the supervision of a medical professional. Do not self-administer and stick to the dosage and other instructions laid down by the expert.

• People with liver and kidney ailments should consult their doctor, as these drugs play an essential role in the metabolism and elimination of the drug.

• Individuals with neurological conditions such as seizures must discuss with their healthcare provider before using these drugs.

• Ivermectin and Fenbendazole may interact with other drugs. Therefore, you let your doctor know of all the medications you might be taking, particularly any blood thinners, antifungal drugs, immunosuppressants, and antibiotics.

• If you are pregnant or a breastfeeding female, you must exercise control as these drugs may pose a risk to the fetus and the newborn. Therefore, you must consult your doctor.

• You must limit your alcohol intake while on these drugs since it might impact their efficacy and increase the risk of adverse effects.

Conclusion

Treating cancer is quite complex, and it has to be tailored depending on the individual’s condition and their response to the treatment. Recently, Ivermectin and Fenbendazole have drawn much attention due to their promising results in pre-clinical trials. However, these medications have not yet been approved by healthcare professionals. They still have to undergo clinical trials, and further, more concrete studies are required to understand their mechanism, dosage, and safety for cancer patients. These drugs are still being studied, and their long-term impact on humans is yet to be defined. Since these drugs are not yet approved, you must opt for these only if recommended by an expert. They should not be treated as an alternative to the existing treatment against this deadly disease. Please consult your doctor to know the pros and cons of these drugs before you start taking them. Let’s hope that these drugs pass all the necessary steps and can be a game changer in dealing with cancer.