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Sinemet is a combination medication that is used to treat symptoms of Parkinson’s disease, that is caused by low levels of a chemical called dopamine in the brain.
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The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional. It should not be understood to indicate that the use of this medicine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.
Do not use generic carbidopa and levodopa if you have used a MAO inhibitor in the past 2 weeks as it can occur a dangerous drug interaction. MAO inhibitors include; isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine and others.
You should not use this medication if you have narrow-angle glaucoma.
Call your doctor at once if you have:
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
worsening of tremors (uncontrolled shaking);
severe or ongoing vomiting or diarrhea;
confusion, hallucinations, unusual changes in mood or behavior;
depression or suicidal thoughts; or
severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
Some people taking Sinemet have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.
You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.
Common side effects may include:
jerky or twisting muscle movements;
muscle contractions; or
Sinemet should be taken with or without food. Take your doses at regular intervals.
Do not crush, break or chew the tablet, swallow it whole.
It can take up to weeks for this medicine to show significant results in improving your symptoms. But if even after weeks your manifestations do not improve, contact your doctor.
If you are prescribed this medication for a long time, you may need frequent medical tests.
Store at room temperature away from moisture, heat and light.
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