Sirolimus is used with other drugs to prevent organ rejection after a kidney transplant. It works by weakening the immune system of a person to help keep it from rejecting a transplanted organ such as a kidney.
Apart from this, it is also used to treat a rare lung disorder called lymphangioleiomyomatosis that usually happens in women.
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The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional. It should not be understood to indicate that the use of this medicine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.
Do not use generic sirolimus 1mg tablets if you have just had a lung transplant or liver transplant.
This medicine may cause your body to overproduce white blood cells that can lead to cancer, severe brain infection.
Call your doctor immediately if you witness fever, flu symptoms, burning when you urinate, a new skin lesion, any change in your mental state, decreased vision, weakness on one side of your body, problems with speech or walking, or pain around your transplant.
Get emergency medical help if you have signs of an allergic reaction: hives, rash, or peeling skin; wheezing, difficulty breathing, chest pain or tightness; feeling like you might pass out; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
redness, oozing, or slow healing of a skin wound;
a new skin lesion, or a mole that has changed in size or color;
unusual bleeding or bruising;
sudden chest pain or discomfort, cough, feeling short of breath;
tenderness around the transplanted kidney;
signs of infection--fever, chills, painful mouth sores, skin sores, cold or flu symptoms, pain or burning when you urinate; or
low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Common side effects may include:
fever, cold symptoms such as stuffy nose, sneezing, sore throat;
nausea, stomach pain, diarrhea;
headache, muscle aches;
Sirolimus is usually take once in a day.
Take cyclosporine at least 4 hours before you take sirolimus.
You can take this medicine with or without food.
Do not suddenly stop taking this medicine without consulting your doctor.
Store it at room temperature away from heat, moisture and light.
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